CMS

CMS may refer to.:

• Centers for Medicare and Medicaid Services, a federal agency in the United States, part of the Department of Health and Human Services
• The Chicago Manual of Style, a style guide for American English
• Compact mass spectrometer
• Contact management system, an integrated office solution to record relationships and interactions with customers and suppliers
• Content management software, a system for managing digital content and providing it in various formats
• Course management system, also known as a learning management system or virtual learning environment