Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig5 Lukauskas BMCBioinformatics2016 17-Supp16.gif|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Huang iScience2022 25-8.jpg|240px]]</div>
'''"[[Journal:DGW: An exploratory data analysis tool for clustering and visualisation of epigenomic marks|DGW: An exploratory data analysis tool for clustering and visualisation of epigenomic marks]]"'''
'''"[[Journal:Elegancy: Digitizing the wisdom from laboratories to the cloud with free no-code platform|Elegancy: Digitizing the wisdom from laboratories to the cloud with free no-code platform]]"'''


Functional [[Genomics|genomic]] and epigenomic research relies fundamentally on [[sequencing]]-based methods like ChIP-seq for the detection of DNA-protein interactions. These techniques return large, high-dimensional data sets with visually complex structures, such as multi-modal peaks extended over large genomic regions. Current tools for visualisation and data exploration represent and leverage these complex features only to a limited extent.
One of the top priorities in any [[laboratory]] is [[Archival informatics|archiving]] experimental data in the most secure, efficient, and errorless way. It is especially important to those in chemical and biological research, for it is more likely to damage experiment records. In addition, the transmission of experiment results from paper to electronic devices is time-consuming and redundant. Therefore, we introduce an [[Open-source software|open-source]] no-code [[electronic laboratory notebook]] (ELN), Elegancy, a [[Cloud computing|cloud-based]]/standalone web service distributed as a Docker image. Elegancy fits all laboratories but is specially equipped with several features benefitting biochemical laboratories. It can be accessed via various web browsers, allowing researchers to upload photos or audio recordings directly from their mobile devices. Elegancy also contains a meeting arrangement module, audit/revision control, and laboratory supply management system. We believe Elegancy could help the scientific research community gather evidence, share information, reorganize knowledge, and digitize laboratory works with greater ease and security ... ('''[[Journal:Elegancy: Digitizing the wisdom from laboratories to the cloud with free no-code platform|Full article...]]''')<br />
 
We present DGW (Dynamic Gene Warping), an open-source software package for simultaneous alignment and clustering of multiple epigenomic marks. DGW uses dynamic time warping to adaptively rescale and align genomic distances which allows to group regions of interest with similar shapes, thereby capturing the structure of epigenomic marks. We demonstrate the effectiveness of the approach in a simulation study and on a real epigenomic data set from the ENCODE project. ('''[[Journal:DGW: An exploratory data analysis tool for clustering and visualisation of epigenomic marks|Full article...]]''')<br />
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Latest revision as of 17:08, 10 April 2023

Fig1 Huang iScience2022 25-8.jpg

"Elegancy: Digitizing the wisdom from laboratories to the cloud with free no-code platform"

One of the top priorities in any laboratory is archiving experimental data in the most secure, efficient, and errorless way. It is especially important to those in chemical and biological research, for it is more likely to damage experiment records. In addition, the transmission of experiment results from paper to electronic devices is time-consuming and redundant. Therefore, we introduce an open-source no-code electronic laboratory notebook (ELN), Elegancy, a cloud-based/standalone web service distributed as a Docker image. Elegancy fits all laboratories but is specially equipped with several features benefitting biochemical laboratories. It can be accessed via various web browsers, allowing researchers to upload photos or audio recordings directly from their mobile devices. Elegancy also contains a meeting arrangement module, audit/revision control, and laboratory supply management system. We believe Elegancy could help the scientific research community gather evidence, share information, reorganize knowledge, and digitize laboratory works with greater ease and security ... (Full article...)

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