Difference between revisions of "Sapio Sciences, LLC"

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   |framestyle=border:none; padding:0;
   |framestyle=border:none; padding:0;
   |title=<small>Products list</small>
   |title=<small>Products list</small>
   |1=<li>Exemplar Bioanalytical LIMS
   |1=<li>Sapio Bioanalytical LIMS
   |2=<li>Exemplar Clinical LIMS
   |2=<li>Sapio Clinical LIMS
   |3=<li>Exemplar ELN
   |3=<li>Sapio Seamless ELN
   |4=<li>Exemplar Histopathology LIMS
   |4=<li>Saoui Histopathology LIMS
   |5=<li>Exemplar NGS LIMS
   |5=<li>Sapio NGS LIMS
   |6=<li>Exemplar Research LIMS
   |6=<li>Sapio Research LIMS
   |7=<li>Exemplar Stability LIMS
   |7=<li>Sapio Stability LIMS
   }}
   }}
|production        =
|production        =
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|divisions        =
|divisions        =
|subsid            =
|subsid            =
|homepage          =  [https://www.sapiosciences.com/ SapioSciences.com]<br />[https://exemplareln.com/ exemplareln.com]
|homepage          =  [https://www.sapiosciences.com/ SapioSciences.com]
|linkedin          =  [https://www.linkedin.com/company/sapio-sciences-llc/ https://www.linkedin.com/company/sapio-sciences-llc/]
|linkedin          =  [https://www.linkedin.com/company/sapio-sciences-llc/ https://www.linkedin.com/company/sapio-sciences-llc/]
|footnotes        =
|footnotes        =
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Sapio Sciences was originally founded in 2004 to develop software tools to address the growing genotyping need for tools to assist in analyzing genetics data, particularly in relation to Genome Wide Association Studies. Sapio's first product was Exemplar Analytics, which ultimately incorporated over 50 different algorithms and was utilized in numerous published papers.<ref>{{cite journal |pmc=2582197 |pmid=19005574 |year=2008 |last1=Shiels |first1=A |last2=Bennett |first2=TM |last3=Knopf |first3=HL |last4=Maraini |first4=G |last5=Li |first5=A |last6=Jiao |first6=X |last7=Hejtmancik |first7=JF |title=The EPHA2 gene is associated with cataracts linked to chromosome 1p |volume=14 |pages=2042–55 |journal=Molecular vision}}</ref><ref>{{cite journal |doi=10.1371/journal.pgen.1000218 |title=Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis |year=2008 |editor1-last=Gojobori |editor1-first=Takashi |last1=Davila |first1=Sonia |last2=Hibberd |first2=Martin L. |last3=Hari Dass |first3=Ranjeeta |last4=Wong |first4=Hazel E. E. |last5=Sahiratmadja |first5=Edhyana |last6=Bonnard |first6=Carine |last7=Alisjahbana |first7=Bachti |last8=Szeszko |first8=Jeffrey S. |last9=Balabanova |first9=Yanina |journal=PLoS Genetics |volume=4 |issue=10 |pages=e1000218 |pmid=18927625 |pmc=2568981}}</ref><ref>{{cite journal |pmc=2493541 |pmid=18453595 |year=2008 |last1=Mattapallil |first1=MJ |last2=Sahin |first2=A |last3=Silver |first3=PB |last4=Sun |first4=SH |last5=Chan |first5=CC |last6=Remmers |first6=EF |last7=Hejtmancik |first7=JF |last8=Caspi |first8=RR |title=Common genetic determinants of uveitis shared with other autoimmune disorders |volume=180 |issue=10 |pages=6751–9 |journal=Journal of Immunology (Baltimore, Md. : 1950)}}</ref><ref>{{cite journal |pmc=2607021 |doi=10.1371/journal.pgen.1000319 |title=A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease |year=2009 |editor1-last=Gibson |editor1-first=Greg |last1=Burgner |first1=David |last2=Davila |first2=Sonia |last3=Breunis |first3=Willemijn B. |last4=Ng |first4=Sarah B. |last5=Li |first5=Yi |last6=Bonnard |first6=Carine |last7=Ling |first7=Ling |last8=Wright |first8=Victoria J. |last9=Thalamuthu |first9=Anbupalam |journal=PLoS Genetics |volume=5 |pages=e1000319 |pmid=19132087 |issue=1}}</ref><ref>{{cite journal |doi=10.1038/ng1809 |title=A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia |year=2006 |last1=Horvath |first1=Anelia |last2=Boikos |first2=Sosipatros |last3=Giatzakis |first3=Christoforos |last4=Robinson-White |first4=Audrey |last5=Groussin |first5=Lionel |last6=Griffin |first6=Kurt J |last7=Stein |first7=Erica |last8=Levine |first8=Elizabeth |last9=Delimpasi |first9=Georgia |journal=Nature Genetics |volume=38 |issue=7 |pages=794–800 |pmid=16767104}}</ref> Sapio was subsequently approached by several customers to develop a [[LIMS]] solution that would provide a greater level of flexibility and configurability than traditional LIMS solutions on the market. This led to the development of Exemplar LIMS and its introduction in early 2007.<ref name="SapioExemp07">{{cite web |url=http://www.limsfinder.com/BlogDetail.aspx?id=32034_0_3_0_C |archiveurl=https://www.limsforum.com/sapio-sciences-announces-top-5-pharma-licenses-exemplar-lims/51178/ |title=Sapio Sciences Announces Top 5 Pharma Licenses Exemplar LIMS |publisher=LIMSfinder.com |date=22 April 2007 |archivedate=22 April 2007 |accessdate=01 June 2020}}</ref>
Sapio Sciences was originally founded in 2004 to develop software tools to address the growing genotyping need for tools to assist in analyzing genetics data, particularly in relation to Genome Wide Association Studies. Sapio's first product was Exemplar Analytics, which ultimately incorporated over 50 different algorithms and was utilized in numerous published papers.<ref>{{cite journal |pmc=2582197 |pmid=19005574 |year=2008 |last1=Shiels |first1=A |last2=Bennett |first2=TM |last3=Knopf |first3=HL |last4=Maraini |first4=G |last5=Li |first5=A |last6=Jiao |first6=X |last7=Hejtmancik |first7=JF |title=The EPHA2 gene is associated with cataracts linked to chromosome 1p |volume=14 |pages=2042–55 |journal=Molecular vision}}</ref><ref>{{cite journal |doi=10.1371/journal.pgen.1000218 |title=Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis |year=2008 |editor1-last=Gojobori |editor1-first=Takashi |last1=Davila |first1=Sonia |last2=Hibberd |first2=Martin L. |last3=Hari Dass |first3=Ranjeeta |last4=Wong |first4=Hazel E. E. |last5=Sahiratmadja |first5=Edhyana |last6=Bonnard |first6=Carine |last7=Alisjahbana |first7=Bachti |last8=Szeszko |first8=Jeffrey S. |last9=Balabanova |first9=Yanina |journal=PLoS Genetics |volume=4 |issue=10 |pages=e1000218 |pmid=18927625 |pmc=2568981}}</ref><ref>{{cite journal |pmc=2493541 |pmid=18453595 |year=2008 |last1=Mattapallil |first1=MJ |last2=Sahin |first2=A |last3=Silver |first3=PB |last4=Sun |first4=SH |last5=Chan |first5=CC |last6=Remmers |first6=EF |last7=Hejtmancik |first7=JF |last8=Caspi |first8=RR |title=Common genetic determinants of uveitis shared with other autoimmune disorders |volume=180 |issue=10 |pages=6751–9 |journal=Journal of Immunology (Baltimore, Md. : 1950)}}</ref><ref>{{cite journal |pmc=2607021 |doi=10.1371/journal.pgen.1000319 |title=A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease |year=2009 |editor1-last=Gibson |editor1-first=Greg |last1=Burgner |first1=David |last2=Davila |first2=Sonia |last3=Breunis |first3=Willemijn B. |last4=Ng |first4=Sarah B. |last5=Li |first5=Yi |last6=Bonnard |first6=Carine |last7=Ling |first7=Ling |last8=Wright |first8=Victoria J. |last9=Thalamuthu |first9=Anbupalam |journal=PLoS Genetics |volume=5 |pages=e1000319 |pmid=19132087 |issue=1}}</ref><ref>{{cite journal |doi=10.1038/ng1809 |title=A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia |year=2006 |last1=Horvath |first1=Anelia |last2=Boikos |first2=Sosipatros |last3=Giatzakis |first3=Christoforos |last4=Robinson-White |first4=Audrey |last5=Groussin |first5=Lionel |last6=Griffin |first6=Kurt J |last7=Stein |first7=Erica |last8=Levine |first8=Elizabeth |last9=Delimpasi |first9=Georgia |journal=Nature Genetics |volume=38 |issue=7 |pages=794–800 |pmid=16767104}}</ref> Sapio was subsequently approached by several customers to develop a [[LIMS]] solution that would provide a greater level of flexibility and configurability than traditional LIMS solutions on the market. This led to the development of Exemplar LIMS and its introduction in early 2007.<ref name="SapioExemp07">{{cite web |url=http://www.limsfinder.com/BlogDetail.aspx?id=32034_0_3_0_C |archiveurl=https://www.limsforum.com/sapio-sciences-announces-top-5-pharma-licenses-exemplar-lims/51178/ |title=Sapio Sciences Announces Top 5 Pharma Licenses Exemplar LIMS |publisher=LIMSfinder.com |date=22 April 2007 |archivedate=22 April 2007 |accessdate=01 June 2020}}</ref>


Sapio quietly discontinued its Examplar Biomarker Discovery product sometime after November 2014.<ref name="SapioProdsArch">{{cite web |url=http://www.sapiosciences.com/lims_products.php |archiveurl=https://web.archive.org/web/20141104122256/http://www.sapiosciences.com/lims_products.php |title=Sapio's Laboratory Information Management (LIMS) Solutions |publisher=Sapio Sciences, LLC |date=2014 |archivedate=04 November 2014 |accessdate=14 October 2015}}</ref>
Sapio introduced its Workflow Engine in 2008<ref name="Sapio2008">{{cite web |url=http://www.bio-itworld.com/2012/02/22/eln-excellence-new-lab-notebooks.html |title=ELN Excellence: The New Lab Notebooks |author=Proffitt, Allison |work=Bio IT World |publisher=Cambridge Healthtech Institute |date=22 February 2012 |accessdate=30 September 2013}}</ref>, with the goal of being able to address the [[electronic laboratory notebook]] market and eliminate paper based recording of lab process information.


==Technology and products==
Sapio subsequently added a fully configurable data model to the Examplar platform, which meant that Exemplar could now track virtually any data assuming reasonable constraints on volume.<ref name="SciComp40">{{cite web |url=http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx |archiveurl=https://web.archive.org/web/20120311231308/http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx |title=Sapio Sciences Exemplar LIMS 4.0 |publisher=Scientific Computing |date=15 June 2010 |archivedate=11 March 2012 |accessdate=01 June 2020}}</ref> This has led to Exemplar being used as a [[scientific data management system]] (SDMS), managing large volumes of targeted assay data. Statistics were also be implemented to perform detailed analysis of scientific data within the same environment.
Exemplar is a versatile software suite that encompasses [[Laboratory information management system|laboratory information management]], [[electronic laboratory notebook]], molecular diagnostics, biomarker discovery, and data management in a single framework.<ref name="ExempAbout">{{cite web |url=https://www.sapiosciences.com/about-us |title=About Us |publisher=Sapio Sciences, LLC |accessdate=14 October 2015}}</ref> Since its original introduction in 2007, Exemplar has evolved into more than a [[LIMS]] solution. Sapio introduced its Workflow Engine in 2008<ref name="Sapio2008">{{cite web |url=http://www.bio-itworld.com/2012/02/22/eln-excellence-new-lab-notebooks.html |title=ELN Excellence: The New Lab Notebooks |author=Proffitt, Allison |work=Bio IT World |publisher=Cambridge Healthtech Institute |date=22 February 2012 |accessdate=30 September 2013}}</ref>, with the goal of being able to address the [[electronic laboratory notebook]] market and eliminate paper based recording of lab process information.


Exemplar subsequently added a fully configurable data model which meant that Exemplar could now track virtually any data assuming reasonable constraints on volume.<ref name="SciComp40">{{cite web |url=http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx |archiveurl=https://web.archive.org/web/20120311231308/http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx |title=Sapio Sciences Exemplar LIMS 4.0 |publisher=Scientific Computing |date=15 June 2010 |archivedate=11 March 2012 |accessdate=01 June 2020}}</ref> This has led to Exemplar being used as a [[scientific data management system]] (SDMS) where it is used to manage large volumes of targeted assay data. Statistics have also be implemented to perform detailed analysis of scientific data within the same environment.
Sapio quietly discontinued its Examplar Biomarker Discovery product sometime after November 2014.<ref name="SapioProdsArch">{{cite web |url=http://www.sapiosciences.com/lims_products.php |archiveurl=https://web.archive.org/web/20141104122256/http://www.sapiosciences.com/lims_products.php |title=Sapio's Laboratory Information Management (LIMS) Solutions |publisher=Sapio Sciences, LLC |date=2014 |archivedate=04 November 2014 |accessdate=14 October 2015}}</ref>


In November 2015, Sapio announced its NGS LIMS was available hosted in the cloud under the [[software as a service]] distribution model.<ref name="SapioNGSSaaS">{{cite web |url=https://www.sapiosciences.com/news/Sapio-Announces-Exemplar-NGS-LIMS-2-0-with-Hosted-Option |title=Sapio Announces Exemplar NGS LIMS 2.0 with Hosted Option |publisher=Sapio Sciences, LLC |date=10 November 2015 |accessdate=27 July 2016}}</ref> Its other solutions soon followed as being able to be hosted locally or in the cloud.
In November 2015, Sapio announced its NGS LIMS was available hosted in the cloud under the [[software as a service]] distribution model.<ref name="SapioNGSSaaS">{{cite web |url=https://www.sapiosciences.com/news/Sapio-Announces-Exemplar-NGS-LIMS-2-0-with-Hosted-Option |title=Sapio Announces Exemplar NGS LIMS 2.0 with Hosted Option |publisher=Sapio Sciences, LLC |date=10 November 2015 |accessdate=27 July 2016}}</ref> Its other solutions soon followed as being able to be hosted locally or in the cloud.


===Product architecture===
Sometime in the summer or fall of 2021, Sapio Sciences dropped the "Exemplar" name from its products and replaced it with "Sapio."<ref name="SapioExemplarClinArch">{{cite web |url=https://www.sapiosciences.com/clinical-lims-software |archiveurl=https://web.archive.org/web/20210629184634/https://www.sapiosciences.com/clinical-lims-software |title=Exemplar Clinical LIMS Software |publisher=Sapio Sciences, LLC |archivedate=29 June 2021 |accessdate=07 October 2021}}</ref><ref name="SapioExemplarELNArch">{{cite web |url=https://www.sapiosciences.com/electronic-lab-notebook-software-eln |archiveurl=https://web.archive.org/web/20210629190901/https://www.sapiosciences.com/electronic-lab-notebook-software-eln |title=Exemplar Seamless ELN |publisher=Sapio Sciences, LLC |archivedate=29 June 2021 |accessdate=07 October 2021}}</ref>
Exemplar is an n-tier product that offers both Java and web-based clients. Multiple databases are supported for data storage including MySQL and Oracle.


===Target markets===
==Technology and products==
The general framework and adaptable nature of Exemplar has made it applicable to a broad spectrum of accounts, ranging from large pharmaceuticals to university R&D departments. Exemplar is also being used in highly regulated environments such as [[21 CFR Part 11|part 11]], GLP, and [[CLIA]] laboratories.<ref>{{cite web |url=http://www.bio-itworld.com/issues/2008/oct/exonhit.html |title=ExonHit Bets on Sapio LIMS |author=Russell, J. |publisher=Bio-IT World |date=8 October 2008 |accessdate=29 May 2013}}</ref> The Exemplar family of products are focused on supporting non-profit research labs, commercial entities engaging in the discovery of biomarkers, and commercial companies applying ready-for-market molecular based diagnostics.<ref name="40Brochure">{{cite web |url=https://www.sapiosciences.com/news/Sapio-Sciences-Exemplar-LIMS-4-0-Released |title=Sapio Sciences Exemplar LIMS 4.0 Released |publisher=Sapio Sciences, LLC |date=17 May 2010 |accessdate=01 June 2020}}</ref>
The Sapio software suite encompasses [[Laboratory information management system|laboratory information management]], [[electronic laboratory notebook]], molecular diagnostics, and data management in a single framework.<ref name="ExempAbout">{{cite web |url=https://www.sapiosciences.com/about-us |title=About Us |publisher=Sapio Sciences, LLC |accessdate=14 October 2015}}</ref> Since its original introduction in 2007 as "Exemplar," this suite of application has evolved into more than a LIMS solution. The general framework and adaptable nature of the Sapio suite has made it applicable to a broad spectrum of accounts, ranging from large pharmaceuticals to university R&D departments. Over the years, Sapio has also been used in highly regulated environments such as [[21 CFR Part 11|part 11]], GLP, and [[CLIA]] laboratories.<ref>{{cite web |url=http://www.bio-itworld.com/issues/2008/oct/exonhit.html |archiveurl=https://web.archive.org/web/20201030213313/http://www.bio-itworld.com/issues/2008/oct/exonhit.html |title=ExonHit Bets on Sapio LIMS |author=Russell, J. |publisher=Bio-IT World |archivedate=30 October 2020 |date=8 October 2008 |accessdate=29 May 2013}}</ref>


===Features===
===Features===
'''Note''': As of June 2020, Sapio laboratory informatics solutions include LIMS for research, diagnostics, next-generation sequencing, stability studies, histopathology, and bioanalysis, as well as an ELN. Due to space constraints, feature tables for some of them do not appear below. More specifically, see the vendor pages for [https://www.sapiosciences.com/exemplar-histopathology-lims Exemplar Histopathology LIMS], [https://www.sapiosciences.com/exemplar-bioanalytical-lims Bioanalytical LIMS], and [https://www.sapiosciences.com/exemplar-stability-lims Stability LIMS] for more about those specific solutions.
'''Note''': As of October 2021, Sapio laboratory informatics solutions include LIMS for research, diagnostics, next-generation sequencing, stability studies, histopathology, and bioanalysis, as well as an ELN. Due to space constraints, feature tables for some of them do not appear below. More specifically, see the vendor pages for [https://www.sapiosciences.com/sapio-histopathology-lims Sapio Histopathology LIMS], [https://www.sapiosciences.com/sapio-bioanalytical-lims Bioanalytical LIMS], and [https://www.sapiosciences.com/sapio-stability-lims Stability LIMS] for more about those specific solutions.


{{Ombox productfeature}}
{{Ombox productfeature}}
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{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
  |-
  |-
   ! colspan="2"| Product: [https://www.sapiosciences.com/clinical-lims-software Exemplar Clinical LIMS]
   ! colspan="2"| Product: [https://www.sapiosciences.com/clinical-lims-software Sapio Clinical LIMS]
  |-
  |-
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
| sample_login_man  = Y<ref name="SapioDXAbout">{{cite web |url=https://www.sapiosciences.com/clinical-lims-software |title=Exemplar Clinical LIMS |publisher=Sapio Sciences, LLC |date=2020 |accessdate=18 August 2020}}</ref>
| sample_login_man  = Y<ref name="SapioDXAbout">{{cite web |url=https://www.sapiosciences.com/clinical-lims-software |title=Sapio Clinical LIMS |publisher=Sapio Sciences, LLC |date=2021 |accessdate=07 October 2021}}</ref>
| sample_track      = Y<ref name="SapioDXAbout" />
| sample_track      = Y<ref name="SapioDXAbout" />
| sample_batch      =  
| sample_batch      =  
Line 146: Line 144:
| saas_model        = Y<ref name="SapioHome">{{cite web |url=https://www.sapiosciences.com/ |title=Sapio Sciences |publisher=Sapio Sciences, LLC |accessdate=01 June 2020}}</ref>
| saas_model        = Y<ref name="SapioHome">{{cite web |url=https://www.sapiosciences.com/ |title=Sapio Sciences |publisher=Sapio Sciences, LLC |accessdate=01 June 2020}}</ref>
| usage_cost        =  
| usage_cost        =  
| industries        = life sciences
| industries        = clinical diagnostics
}}
}}
  |-
  |-
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{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
  |-
  |-
   ! colspan="2"| Product: [https://www.sapiosciences.com/electronic-lab-notebook-software-eln Exemplar ELN]
   ! colspan="2"| Product: [https://www.sapiosciences.com/electronic-lab-notebook-software-eln Sapio Seamless ELN]
  |-
  |-
   | style="background-color:white; border-style:none;"| {{Databox ELNfeature
   | style="background-color:white; border-style:none;"| {{Databox ELNfeature
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| chem_spec_file    =  
| chem_spec_file    =  
| task_event_sched  =  
| task_event_sched  =  
| manual_entry      = Y<ref name="SapioELNAbout">{{cite web |url=https://www.sapiosciences.com/electronic-lab-notebook-software-eln |title=Exemplar ELN |publisher=Sapio Sciences, LLC |accessdate=18 August 2020}}</ref>
| manual_entry      = Y<ref name="SapioELNAbout">{{cite web |url=https://www.sapiosciences.com/electronic-lab-notebook-software-eln |title=Sapio Seamless ELN |publisher=Sapio Sciences, LLC |accessdate=07 October 2021}}</ref>
| multiple_view      = Y<ref name="SapioELNAbout" />
| multiple_view      = Y<ref name="SapioELNAbout" />
| data_analysis      = Y<ref name="SapioELNAbout" />
| data_analysis      = Y<ref name="SapioELNAbout" />
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| web_client        = Y<ref name="SapioELNAbout" />
| web_client        = Y<ref name="SapioELNAbout" />
| online_help        =  
| online_help        =  
| saas_model        = Y<ref name="SapioELNFeats">{{cite web |url=https://exemplareln.com/eln-features |title=Sapio Sciences Exemplar ELN Editions |publisher=Sapio Sciences, LLC |accessdate=01 June 2020}}</ref>
| saas_model        = Y<ref name="SapioELNAbout" />
| usage_cost        =  
| usage_cost        =  


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{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
  |-
  |-
   ! colspan="2"| Product: [https://www.sapiosciences.com/exemplar-ngs-lims Exemplar NGS LIMS]
   ! colspan="2"| Product: [https://www.sapiosciences.com/sapio-ngs-lims Sapio NGS LIMS]
  |-
  |-
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
| sample_login_man  = Y<ref name="SapioNGSAbout">{{cite web |url=https://www.sapiosciences.com/exemplar-ngs-lims |title=Exemplar NGS LIMS |publisher=Sapio Sciences, LLC |date=2015 |accessdate=14 October 2015}}</ref>
| sample_login_man  = Y<ref name="SapioNGSAbout">{{cite web |url=https://www.sapiosciences.com/sapio-ngs-lims |title=Sapio NGS LIMS |publisher=Sapio Sciences, LLC |date=2021 |accessdate=07 October 2021}}</ref>
| sample_track      = Y<ref name="SapioNGSAbout" />
| sample_track      = Y<ref name="SapioNGSAbout" />
| sample_batch      =  
| sample_batch      =  
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| saas_model        = Y<ref name="SapioNGSSaaS" />
| saas_model        = Y<ref name="SapioNGSSaaS" />
| usage_cost        =  
| usage_cost        =  
| industries        = life sciences
| industries        = high-throughput sequencing
}}
}}
  |-
  |-
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{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
{| class="wikitable collapsible" style="border-style:none;" background="#ffffff" border="0" cellpadding="0" cellspacing="0"
  |-
  |-
   ! colspan="2"| Product: [https://www.sapiosciences.com/exemplar-research-lims Exemplar Research LIMS]
   ! colspan="2"| Product: [https://www.sapiosciences.com/lab-management-software Sapio Research LIMS]
  |-
  |-
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
   | style="background-color:white; border-style:none;"| {{Databox LIMSfeature
| sample_login_man  = Y<ref name="SapioResAbout">{{cite web |url=https://www.sapiosciences.com/exemplar-research-lims |title=Exemplar Research LIMS |publisher=Sapio Sciences, LLC |date=2015 |accessdate=14 October 2015}}</ref>
| sample_login_man  = Y<ref name="SapioResAbout">{{cite web |url=https://www.sapiosciences.com/lab-management-software |title=Sapio Research LIMS |publisher=Sapio Sciences, LLC |date=2021 |accessdate=07 October 2021}}</ref>
| sample_track      = Y<ref name="SapioResAbout" />
| sample_track      = Y<ref name="SapioResAbout" />
| sample_batch      =  
| sample_batch      =  
Line 371: Line 369:
| saas_model        = Y<ref name="SapioHome" />
| saas_model        = Y<ref name="SapioHome" />
| usage_cost        =  
| usage_cost        =  
| industries        = high-throughput sequencing, life sciences
| industries        = clinical research
}}
}}
  |-
  |-
Line 378: Line 376:


===Pricing===
===Pricing===
Sapio only includes pricing for one of the three levels of its ELN. No public pricing for their LIMS exist.
Pricing is not made public.


The ELN is offered in three editions: Bronze, Silver, and Gold. The Bronze package is just the SaaS-based ELN, at $199 a month or $1,956 annually. The Silver and Gold editions' pricing is unknown.<ref name="SapioELNFeats" /> A comparison of the editions can be [https://exemplareln.com/eln-features found here].
====Demonstration videos and other media====
Sapio has the following product demonstration videos on their [https://www.youtube.com/channel/UCSaG6pLXU5EIn51iMcQE6oA YouTube channel]:
 
* [https://www.youtube.com/watch?v=fzYlvU1H_yI Sapio Sciences' Exemplar LIMS - Overview]
* [https://www.youtube.com/watch?v=U5avRTGtER4 Deploying and NGS LIMS for Complex Research and Clinical Environments] (Exemplar NGS LIMS)


===Additional information===
===Additional information===
 
* [https://www.sapiosciences.com/electronic-lab-notebook-editions Sapio Seamless edition comparison]


==References==
==References==
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<!---Place all category tags here-->
<!---Place all category tags here-->
[[Category:Biotechnology LIMS]]
[[Category:Clinical diagnostics LIMS]]
[[Category:Clinical research LIMS]]
[[Category:Clinical research LIMS]]
[[Category:Cloud-based ELN]]
[[Category:Cloud-based ELN]]
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[[Category:General ELN]]
[[Category:General ELN]]
[[Category:High-throughput sequencing LIMS]]
[[Category:High-throughput sequencing LIMS]]
[[Category:Life sciences LIMS]]
[[Category:LIMS vendor]]
[[Category:LIMS vendor]]
[[Category:Pathology LIMS]]
[[Category:Pharmaceutical LIMS]]
[[Category:Pharmaceutical LIMS]]
[[Category:Vendors]]
[[Category:Vendors]]

Latest revision as of 17:35, 2 March 2022

Sapio Sciences, LLC
Type Limited Liability Company
Industry Laboratory informatics
Headquarters Inner Harbor Center, 400 E. Pratt St., Ste. 800, Baltimore, Maryland, U.S.
Number of locations 3
Area served U.S.
Products
Website SapioSciences.com
LinkedIn https://www.linkedin.com/company/sapio-sciences-llc/

Sapio Sciences, LLC develops and distributes laboratory informatics software solutions.


History

Sapio Sciences was originally founded in 2004 to develop software tools to address the growing genotyping need for tools to assist in analyzing genetics data, particularly in relation to Genome Wide Association Studies. Sapio's first product was Exemplar Analytics, which ultimately incorporated over 50 different algorithms and was utilized in numerous published papers.[1][2][3][4][5] Sapio was subsequently approached by several customers to develop a LIMS solution that would provide a greater level of flexibility and configurability than traditional LIMS solutions on the market. This led to the development of Exemplar LIMS and its introduction in early 2007.[6]

Sapio introduced its Workflow Engine in 2008[7], with the goal of being able to address the electronic laboratory notebook market and eliminate paper based recording of lab process information.

Sapio subsequently added a fully configurable data model to the Examplar platform, which meant that Exemplar could now track virtually any data assuming reasonable constraints on volume.[8] This has led to Exemplar being used as a scientific data management system (SDMS), managing large volumes of targeted assay data. Statistics were also be implemented to perform detailed analysis of scientific data within the same environment.

Sapio quietly discontinued its Examplar Biomarker Discovery product sometime after November 2014.[9]

In November 2015, Sapio announced its NGS LIMS was available hosted in the cloud under the software as a service distribution model.[10] Its other solutions soon followed as being able to be hosted locally or in the cloud.

Sometime in the summer or fall of 2021, Sapio Sciences dropped the "Exemplar" name from its products and replaced it with "Sapio."[11][12]

Technology and products

The Sapio software suite encompasses laboratory information management, electronic laboratory notebook, molecular diagnostics, and data management in a single framework.[13] Since its original introduction in 2007 as "Exemplar," this suite of application has evolved into more than a LIMS solution. The general framework and adaptable nature of the Sapio suite has made it applicable to a broad spectrum of accounts, ranging from large pharmaceuticals to university R&D departments. Over the years, Sapio has also been used in highly regulated environments such as part 11, GLP, and CLIA laboratories.[14]

Features

Note: As of October 2021, Sapio laboratory informatics solutions include LIMS for research, diagnostics, next-generation sequencing, stability studies, histopathology, and bioanalysis, as well as an ELN. Due to space constraints, feature tables for some of them do not appear below. More specifically, see the vendor pages for Sapio Histopathology LIMS, Bioanalytical LIMS, and Stability LIMS for more about those specific solutions.

The following feature list(s) is/are derived solely from public, freely-available online information the vendor provides. A lack of a "Y" does not necessarily mean that the product doesn't have that feature. The lack of a "Y" could mean:
  • the vendor chose to not put relevant feature information online despite its existence in the product.
  • the vendor chooses to make the feature information available only to those who create an account or call/e-mail.
  • the feature information exists online to the public, but a URL could not be found to cite the existence of the feature.
  • the feature does not exist for the product.
A vendor's product may receive more confirmed features with the addition of more public information to the vendor's site and/or by providing a URL to a page or document that can act as a citation for the existence of the feature. Prospective buyers are highly recommended to contact the vendor directly to verify features as this list isn't authoritative, and product upgrades and changes happen rapidly in some cases.
Product: Sapio Clinical LIMS
Sample, inventory, and data management
Sample login and management?Y[15]
Sample tracking?Y[15]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?
Data and trend analysis?
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?Y[15]
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?
Document creation and/or management?
Case management?
Workflow management?Y[15]
Specification management?
Customer and supplier management?Y[15]
Billing management?Y[15]
Quality, security, and compliance
Regulatory compliance?Y[15]
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?Y[15]
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[15]
Modular?
Instrument interfacing and management?Y[15]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?Y[16]
Web client or portal?Y[16]
Online or integrated help?
Software as a service delivery model?Y[16]
Usage-based cost?
Industries served
clinical diagnostics
Product: Sapio Seamless ELN
Experiment, collaboration,
and data management
Chemical and/or mathematical drawing and calculation?
Chemical and/or spectrum file support?
Task and event scheduling?
Option for manual result entry?Y[17]
Multiple data viewing methods?Y[17]
Data and trend analysis?Y[17]
Data and equipment sharing?Y[17]
Customizable fields and/or interface?Y[17]
Configurable templates and forms?Y[17]
Query capability?Y[17]
Import data?Y[17]
Internal file or data linking?
External file or data linking?
Export data to MS Excel?
Raw data management?
Data warehouse?
Project and/or task management?
Inventory management?Y[17]
Document creation and/or management?
Lab and/or group management?
Experiment management?
Workflow management?
Customer and supplier management?
Quality, security, and compliance
Regulatory compliance?
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?Y[17]
Data normalization?
Data validation?
Data encryption?
Electronic signatures?Y[17]
Version control?
Automatic data backup?
Reporting, barcoding, and printing
Custom reporting?
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Email integration?
Base functionality
Administrator management?Y[17]
Modular?
Instrument interfacing and management?Y[17]
Mobile device integration?Y[17]
Third-party software integration?Y[17]
Alarms and/or alerts?Y[17]
External monitoring?
Messaging?
Bookmarking?
Commenting?
Multilingual?
Network-capable?Y[16]
Web client or portal?Y[17]
Online or integrated help?
Software as a service delivery model?Y[17]
Usage-based cost?
Industries served
industry-neutral
Product: Sapio NGS LIMS
Sample, inventory, and data management
Sample login and management?Y[18]
Sample tracking?Y[18]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?Y[18]
Data and trend analysis?
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?Y[18]
Document creation and/or management?
Case management?
Workflow management?Y[18]
Specification management?
Customer and supplier management?
Billing management?
Quality, security, and compliance
Regulatory compliance?Y[18]
QA / QC functions?Y[18]
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[18]
Modular?
Instrument interfacing and management?Y[18]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?Y[16]
Web client or portal?Y[18]
Online or integrated help?
Software as a service delivery model?Y[10]
Usage-based cost?
Industries served
high-throughput sequencing
Product: Sapio Research LIMS
Sample, inventory, and data management
Sample login and management?Y[19]
Sample tracking?Y[19]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?
Data and trend analysis?Y[19]
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?Y[19]
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?Y[19]
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?
Document creation and/or management?
Case management?
Workflow management?Y[19]
Specification management?Y[19]
Customer and supplier management?
Billing management?
Quality, security, and compliance
Regulatory compliance?
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?Y[19]
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[19]
Modular?
Instrument interfacing and management?Y[19]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?Y[16]
Web client or portal?Y[16]
Online or integrated help?
Software as a service delivery model?Y[16]
Usage-based cost?
Industries served
clinical research

Pricing

Pricing is not made public.

Demonstration videos and other media

Sapio has the following product demonstration videos on their YouTube channel:

Additional information

References

  1. ↑ Shiels, A; Bennett, TM; Knopf, HL; Maraini, G; Li, A; Jiao, X; Hejtmancik, JF (2008). "The EPHA2 gene is associated with cataracts linked to chromosome 1p". Molecular vision 14: 2042–55. PMC 2582197. PMID 19005574. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2582197. 
  2. ↑ Davila, Sonia; Hibberd, Martin L.; Hari Dass, Ranjeeta; Wong, Hazel E. E.; Sahiratmadja, Edhyana; Bonnard, Carine; Alisjahbana, Bachti; Szeszko, Jeffrey S. et al. (2008). Gojobori, Takashi. ed. "Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis". PLoS Genetics 4 (10): e1000218. doi:10.1371/journal.pgen.1000218. PMC 2568981. PMID 18927625. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2568981. 
  3. ↑ Mattapallil, MJ; Sahin, A; Silver, PB; Sun, SH; Chan, CC; Remmers, EF; Hejtmancik, JF; Caspi, RR (2008). "Common genetic determinants of uveitis shared with other autoimmune disorders". Journal of Immunology (Baltimore, Md. : 1950) 180 (10): 6751–9. PMC 2493541. PMID 18453595. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2493541. 
  4. ↑ Burgner, David; Davila, Sonia; Breunis, Willemijn B.; Ng, Sarah B.; Li, Yi; Bonnard, Carine; Ling, Ling; Wright, Victoria J. et al. (2009). Gibson, Greg. ed. "A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease". PLoS Genetics 5 (1): e1000319. doi:10.1371/journal.pgen.1000319. PMC 2607021. PMID 19132087. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2607021. 
  5. ↑ Horvath, Anelia; Boikos, Sosipatros; Giatzakis, Christoforos; Robinson-White, Audrey; Groussin, Lionel; Griffin, Kurt J; Stein, Erica; Levine, Elizabeth et al. (2006). "A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia". Nature Genetics 38 (7): 794–800. doi:10.1038/ng1809. PMID 16767104. 
  6. ↑ "Sapio Sciences Announces Top 5 Pharma Licenses Exemplar LIMS". LIMSfinder.com. 22 April 2007. Archived from the original on 22 April 2007. https://www.limsforum.com/sapio-sciences-announces-top-5-pharma-licenses-exemplar-lims/51178/. Retrieved 01 June 2020. 
  7. ↑ Proffitt, Allison (22 February 2012). "ELN Excellence: The New Lab Notebooks". Bio IT World. Cambridge Healthtech Institute. http://www.bio-itworld.com/2012/02/22/eln-excellence-new-lab-notebooks.html. Retrieved 30 September 2013. 
  8. ↑ "Sapio Sciences Exemplar LIMS 4.0". Scientific Computing. 15 June 2010. Archived from the original on 11 March 2012. https://web.archive.org/web/20120311231308/http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx. Retrieved 01 June 2020. 
  9. ↑ "Sapio's Laboratory Information Management (LIMS) Solutions". Sapio Sciences, LLC. 2014. Archived from the original on 04 November 2014. https://web.archive.org/web/20141104122256/http://www.sapiosciences.com/lims_products.php. Retrieved 14 October 2015. 
  10. ↑ 10.0 10.1 "Sapio Announces Exemplar NGS LIMS 2.0 with Hosted Option". Sapio Sciences, LLC. 10 November 2015. https://www.sapiosciences.com/news/Sapio-Announces-Exemplar-NGS-LIMS-2-0-with-Hosted-Option. Retrieved 27 July 2016. 
  11. ↑ "Exemplar Clinical LIMS Software". Sapio Sciences, LLC. Archived from the original on 29 June 2021. https://web.archive.org/web/20210629184634/https://www.sapiosciences.com/clinical-lims-software. Retrieved 07 October 2021. 
  12. ↑ "Exemplar Seamless ELN". Sapio Sciences, LLC. Archived from the original on 29 June 2021. https://web.archive.org/web/20210629190901/https://www.sapiosciences.com/electronic-lab-notebook-software-eln. Retrieved 07 October 2021. 
  13. ↑ "About Us". Sapio Sciences, LLC. https://www.sapiosciences.com/about-us. Retrieved 14 October 2015. 
  14. ↑ Russell, J. (8 October 2008). "ExonHit Bets on Sapio LIMS". Bio-IT World. Archived from the original on 30 October 2020. https://web.archive.org/web/20201030213313/http://www.bio-itworld.com/issues/2008/oct/exonhit.html. Retrieved 29 May 2013. 
  15. ↑ 15.0 15.1 15.2 15.3 15.4 15.5 15.6 15.7 15.8 15.9 "Sapio Clinical LIMS". Sapio Sciences, LLC. 2021. https://www.sapiosciences.com/clinical-lims-software. Retrieved 07 October 2021. 
  16. ↑ 16.0 16.1 16.2 16.3 16.4 16.5 16.6 16.7 "Sapio Sciences". Sapio Sciences, LLC. https://www.sapiosciences.com/. Retrieved 01 June 2020. 
  17. ↑ 17.00 17.01 17.02 17.03 17.04 17.05 17.06 17.07 17.08 17.09 17.10 17.11 17.12 17.13 17.14 17.15 17.16 17.17 "Sapio Seamless ELN". Sapio Sciences, LLC. https://www.sapiosciences.com/electronic-lab-notebook-software-eln. Retrieved 07 October 2021. 
  18. ↑ 18.0 18.1 18.2 18.3 18.4 18.5 18.6 18.7 18.8 18.9 "Sapio NGS LIMS". Sapio Sciences, LLC. 2021. https://www.sapiosciences.com/sapio-ngs-lims. Retrieved 07 October 2021. 
  19. ↑ 19.0 19.1 19.2 19.3 19.4 19.5 19.6 19.7 19.8 19.9 "Sapio Research LIMS". Sapio Sciences, LLC. 2021. https://www.sapiosciences.com/lab-management-software. Retrieved 07 October 2021. 
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